Apr 10,  · 酰化反应是化学反应中最常见的一种反应。对于羟基化合物与酸酐的酰化反应，用吡啶作催化剂反应进行温和且可靠，但是当空间位阻较大的醇类进行酰化反应时，反应进行困难，并且产率也比较低。年，Litvinenko和Kirichenko在研究间氯苯胺的苯甲酰化动力学时发现，用4-二甲氨基吡啶(DMAP)作催化剂. Nov 03,  · 酸無水物は反応性の高い分子でアルコールと反応してエステルを生成します。 酸無水物は二分子のカルボン酸の脱水縮合したものですから、アルコールと反応すると一分子はカルボン酸に戻ってしまいます。 したがって、貴重なカルボン酸を. Oct 27,  · Boc2O ( g, mol) in MeOH ( ml) was added toa soluton of compound 1 ( g, mol) in MeOH ( ml) at 10°C,and the resulting mixture was stirred at room temperature for 2 h. N1,N1-dimethylethane-1,2-diamine (26 g, mol) was added and the mixture was stirredat room temperature for 15 min.

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又有人在此基础上加大了即时制备镍硼化物所使用的氯化镍的量，使镍硼化物对腈的摩尔比达到了（即镍硼化物不再是催化剂而成为还原剂了）。但为了避免仲胺的生成，不得不加入醋酐和二碳酸二特丁酯(Boc2O)这样的捕集剂(见图21和下面引用文献). Research. Development. Production. We are a leading supplier to the global Life Science industry with solutions and services for research, biotechnology development and production, and pharmaceutical drug therapy development and production.

Boc2O; Di-tert-butyl Pyrocarbonate; Pyrocarbonic Acid Di-tert-butyl Ester; DiBoc; Boc Anhydride. Documents: SDS | Specifications. Di-tert-butyl Dicarbonate (Boc-anhydride, Boc2O) (English). Mohapatra, Debendra K. New search for: Mohapatra, Debendra K. sample search results ; spacer. Search for: Boc2O. IUPAC Name: tert-butyl (2-methylpropanyl)oxyca CAS Number: Chemical Formula: C10H18O · Search. There are several reagents that can be used for the introduction of Boc groups, such as Boc2O, BocONH2, BocN3, 1-(tert-butoxycarbonyl)benzotriazole. 对水较为敏感的氨基衍生物，采用Boc2O/TEA/MeOH or DMF 在℃下进行较好，因为这些无水条件下用于保护O17标记的氨基酸而不会由于与水交换使O17丢失[2]。有空间位阻的氨基酸而言，用Boc2O /Me4NOH. 5H2O/CH3CN是十分有利的。. 游离氨基酸在碱性条件下（NaOH，NaHCO3）用二氧六环和水的混合试剂可以和Boc2O反应 得到Boc保护的基团。 且副产物容易除去。 Boc脱除. Oct 25,  · boc酸酐是一种有机化合物，分子式为c10h18o5，有机合成中用来引入叔丁氧羰基保护基团。特别运用于氨基酸婡臫的頭樤氨基保护，广泛应用于医药，蛋白质及多肽合成，生物化学食品，化妆品等多种产品的合成中。. Di-tert-butyl dicarbonate; BOC anhydride, Boc2O, di-t-Butyl dicarbonate, Di-tert-butyl pyrocarbonate; MFCD; ;. Boc2O. Di-tert-butyl dicarbonate. Cbz. Benzyloxycarbonyl. DICI. Diisopropylcarbodiimide. DIEA. Diisopropylethylamine. DMF. Dimethylformamide. Boc2O ( mL, mmol, equiv) in dry THF (10 mL) was cooled to 0. ºC in an ice bath. 1,2,3,6-Tetrahydropyridine ( mL, mmol, equiv). I was wondering why Boc2O is highly toxic? Is it due to it's electrophilicity, and thus capability to do protein surface modification?

Tetrahedron Letters 47 () – A rate enhancement of tert-butoxycarbonylation of aromatic amines with Boc2O in alcoholic solvents Tirayut Vilaivan*. Product Name: (Boc)2O (Di-t-Butyl Dicarbonate) Product Number: KBC Synonym(s): Di-tert-butyl dicarbonate, Di-tert-butyl pyrocarbonate, Boc2O. dicarbonate,di-tert-butyl pyrocarbonate,bis tert-butoxycarbonyl oxide,di-tert-butyldicarbonate,boc2o,di-t-butyl pyrocarbonate,di tert-butyl carbonate.